Crossing the divide: a longitudinal study of effective treatments for people with autism and attention deficit hyperactivity disorder across the lifespan.

Journal article


Murphy, D, Glaser, K, Hayward, H, Cadman, T, Findon, J, Woodhouse, E, Ashwood, K, Beecham, J, Bolton, P, McEwan, F, Wilson, E., Ecker, C, Wong, I, Simonoff, E, Russell, A, McCarthy, J, Chaplin, E, Young, S and Asherson, P (2018). Crossing the divide: a longitudinal study of effective treatments for people with autism and attention deficit hyperactivity disorder across the lifespan. Programme Grants for Applied Research. 6 (2), pp. 1-240. https://doi.org/10.3310/pgfar06020
AuthorsMurphy, D, Glaser, K, Hayward, H, Cadman, T, Findon, J, Woodhouse, E, Ashwood, K, Beecham, J, Bolton, P, McEwan, F, Wilson, E., Ecker, C, Wong, I, Simonoff, E, Russell, A, McCarthy, J, Chaplin, E, Young, S and Asherson, P
Abstract

Background: Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) frequently persist into adolescence and young adulthood. However, there are few clinical services that support those with these disorders through adulthood. Objective: Our aim was to determine if clinical services meet the needs of people with ASD and ADHD, who are ‘at transition’ from childhood to adulthood. Design: A longitudinal study of individuals with ASD and ADHD, the impact of services and treatments. Methods: Our research methods included (1) interviewing > 180 affected individuals (and their families) with a confirmed diagnosis of ASD and/or ADHD, (2) screening for ASD and ADHD in approximately 1600 patients and (3) surveying general practitioner prescribing to 5651 ASD individuals across the UK. In addition, we tested the effectiveness of (1) new ASD diagnostic interview measures in 169 twins, 145 families and 150 non-twins, (2) a magnetic resonance imaging-based diagnostic aid in 40 ASD individuals, (3) psychological treatments in 46 ASD individuals and (4) the feasibility of e-learning in 28 clinicians. Setting: NHS clinical services and prisons. Participants: Focus – young people with ASD and ADHD as they ‘transition’ from childhood and adolescence into early adulthood. Interventions: Testing the utility of diagnostic measures and services, web-based learning interventions, pharmacological prescribing and cognitive–behavioural treatments.

Year2018
JournalProgramme Grants for Applied Research
Journal citation6 (2), pp. 1-240
PublisherNIHR Journals Library
ISSN2050-4322
Digital Object Identifier (DOI)https://doi.org/10.3310/pgfar06020
Web address (URL)https://www.journalslibrary.nihr.ac.uk/pgfar/pgfar06020
Publication dates
Print01 Jun 2018
Publication process dates
Deposited23 Jul 2018
Accepted31 Jul 2017
Accepted author manuscript
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